[Extracted from the webpage of actos.com] What is ACTOS ? ACTOS is a once-a-day prescription medication for type 2 diabetes that, along with healthy eating and physical activity, helps your body control blood sugar (glucose) levels . ACTOS makes the cells in your body more sensitive to insulin , a hormone produced by the pancreas that allows the cells in your body to use blood sugar for energy. When the cells are more sensitive to insulin, the sugar that’s in your blood can pass more easily into the cells of your body where it’s really needed. So instead of remaining in the blood, where sugar can build up to dangerous levels, it passes into the cells and your blood sugar levels go down. ACTOS can be used by itself or in combination with certain other diabetes medications ( sulfonylureas , metformin , or insulin) when your necessary efforts at healthy eating and physical activity do not control your blood sugar levels. ACTOS may improve HDL (good) cho...